What are the possible side effects of Jie Ning?
Get emergency medical help if you have signs of an allergic reaction to Jie Ning: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
-
ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions);
-
severe nausea, vomiting, or stomach pain;
-
bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
-
fever lasting longer than 3 days; or
-
swelling, or pain lasting longer than 10 days.
Common Jie Ning side effects may include:
-
upset stomach, heartburn;
-
drowsiness; or
-
mild headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Jie Ning in details
Adverse Reactions
As with all drugs which may affect hemostasis, bleeding is associated with Jie Ning. Hemorrhage may occur at virtually any site. Risk is dependent on multiple variables including dosage, concurrent use of multiple agents which alter hemostasis, and patient susceptibility. Many adverse effects of Jie Ning are dose related, and are rare at low dosages. Other serious reactions are idiosyncratic, related to allergy or individual sensitivity. Accurate estimation of frequencies is not possible. The reactions listed below have been reported for Jie Ning.
Cardiovascular: Cardiac arrhythmia, edema, hypotension, tachycardia
Central nervous system: Agitation, cerebral edema, coma, confusion, dizziness, fatigue, headache, hyperthermia, insomnia, lethargy, nervousness, Reye's syndrome
Dermatologic: Skin rash, urticaria
Endocrine & metabolic: Acidosis, dehydration, hyperglycemia, hyperkalemia, hypernatremia (buffered forms), hypoglycemia (children)
Gastrointestinal: Gastrointestinal ulcer (6% to 31%), duodenal ulcer, dyspepsia, epigastric distress, gastritis, gastrointestinal erosion, heartburn, nausea, stomach pain, vomiting
Genitourinary: Postpartum hemorrhage, prolonged gestation, prolonged labor, proteinuria, stillborn infant
Hematologic & oncologic: Anemia, blood coagulation disorder, disseminated intravascular coagulation, hemolytic anemia, hemorrhage, iron deficiency anemia, prolonged prothrombin time, thrombocytopenia
Hepatic: Hepatitis (reversible), hepatotoxicity, increased serum transaminases
Hypersensitivity: Anaphylaxis, angioedema
Neuromuscular & skeletal: Acetabular bone destruction, rhabdomyolysis, weakness
Otic: Hearing loss, tinnitus
Renal: Increased blood urea nitrogen, increased serum creatinine, interstitial nephritis, renal failure (including cases caused by rhabdomyolysis), renal insufficiency, renal papillary necrosis
Respiratory: Asthma, bronchospasm, dyspnea, hyperventilation, laryngeal edema, noncardiogenic pulmonary edema, respiratory alkalosis, tachypnea
Miscellaneous: Low birth weight
Postmarketing and/or case reports: Anorectal stenosis (suppository), atrial fibrillation (toxicity), cardiac conduction disturbance (toxicity), cerebral infarction (ischemic), cholestatic jaundice, colitis, colonic ulceration, coronary artery vasospasm, delirium, esophageal obstruction, esophagitis (with esophageal ulcer), hematoma (esophageal), macular degeneration (age-related) (Li 2015), periorbital edema, rhinosinusitis
What is the most important information I should know about Jie Ning?
- Do not take Jie Ning for more than 10 days for pain or for more than 3 days for fever unless directed to do so by your health care provider.
- Check with your doctor if fever or pain worsens, redness or swelling is present, or new symptoms occur. If you have a sore throat that is severe, lasts for more than 2 days, or is accompanied or followed by fever, headache, rash, nausea, or vomiting, check with your doctor.
- Jie Ning has Jie Ning in it. Before you start any new medicine, check the label to see if it has Jie Ning in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Jie Ning may have calcium, aluminum, or magnesium in it. Ask your pharmacist which of these ingredients is in Jie Ning.
- Talk to your doctor before you take Jie Ning or other pain relievers/fever reducers if you drink more than 3 drinks with alcohol per day. Serious stomach ulcers or bleeding can occur with the use of Jie Ning. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Jie Ning with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
- Jie Ning may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Jie Ning has been linked to a serious illness called Reye syndrome. Do not give Jie Ning to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
- Tell your doctor or dentist that you take Jie Ning before you receive any medical or dental care, emergency care, or surgery.
- If Jie Ning has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.
- Use Jie Ning with caution in the ELDERLY; they may be more sensitive to its effects, especially those with a blood coagulation disorder.
- Jie Ning should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Jie Ning while you are pregnant. Jie Ning is not recommended during the last 3 months (third trimester) of pregnancy because it may cause harm to the fetus. Jie Ning is found in breast milk. If you are or will be breast-feeding while you use Jie Ning, check with your doctor. Discuss any possible risks to your baby.
Jie Ning contraindications
This medicine is contraindicated in the following situations:
hypersensitivity to Jie Ning or any of the excipients history of asthma provoked by the administration of salicylates or substances of similar activity, including anti-inflammatory drugs, PUD evolving any constitutional or acquired bleeding disorder, risk of bleeding, severe hepatic, severe renal insufficiency, uncontrolled severe heart failure, pregnancy beyond 24 weeks of gestation (5 months of age) at doses above 100 mg per day: beyond 24 weeks of gestation (5 months old), all inhibitors of prostaglandin synthesis may explain the fetus: a cardiopulmonary toxicity (ductus arteriosus and pulmonary hypertension), renal dysfunction may progress to renal failure associated with oligohydramniosIn late pregnancy, the mother and the newborn may have: a prolonged bleeding time due to an anti-platelet aggregation may occur even after administration of low doses of medication inhibiting uterine contractions leading to a delay term or prolonged laborConsequently, Jie Ning is not recommended cons beyond 24 weeks of gestation (5 months old), in combination with methotrexate in doses above 20 mg / week, in combination with oral anticoagulants for anti-inflammatory doses of Jie Ning (> 1 g per dose and / or ? 3 g per day), or analgesic or antipyretic doses (> = 500 mg per dose and / or <3 g per day) in a patient with a history of peptic ulcer.
Due to the presence of lactose, the drug is contraindicated for congenital galactosemia, malabsorption of glucose and galactose deficiency or lactase.
The use of this drug is not recommended during lactation: Jie Ning passing into breast milk, this medicine is not recommended during breastfeeding.
Concomitant use of Jie Ning, with anti-inflammatory doses (> 1 g per dose and / or ? 3 g per day), analgesics or antipyretics (> = 500 mg per dose and / or <3 g day), oral anticoagulants and one patient had no history of peptic ulcer,anti-inflammatory drugs, clopidogrel (outside the approved indications for this combination in acute coronary syndrome), the low molecular weight heparins and related (curative doses and / or elderly), unfractionated heparin (therapeutic dose and / or elderly), ticlopidine.
Reviews
The results of a survey conducted on ndrugs.com for Jie Ning are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Jie Ning. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology